Principal Software Engineer Jobs - December 2025
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CEF AI
AI Innovator
Posted 6 months, 3 weeks ago
CEF AI builds an AI-first data automation platform for secure, decentralized orchestration of agents that compute directly on encrypted data streams. Small team, high ownership, low bureaucracy. Responsibilities: AI Innovator: prototype and ship production AI…
Tech stack
Location
San Francisco (hybrid, remote-first)
Compensation
AI Innovator: $100k–$200k + equity | Principal SWE: $80k–$150k + equity
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CEF AI
AI Innovator
Posted 7 months, 1 week ago
CEF AI builds an AI-first data automation platform for secure, decentralized orchestration of agents that compute directly on encrypted data streams. Small team, high ownership, low bureaucracy. AI Innovator: prototype and ship production AI features quickly;…
Tech stack
Location
San Francisco (hybrid, remote-first)
Compensation
AI Innovator: $100k–$200k + equity; Principal SWE: $80k–$150k + equity
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CEF AI
AI Innovator
Posted 7 months, 2 weeks ago
CEF AI builds an AI-first data automation platform for secure, decentralized orchestration of agents that compute directly on encrypted data streams. Small team, high ownership. AI Innovator: prototype and ship production AI features quickly; extend multi-age…
Tech stack
Location
San Francisco (hybrid, remote-first)
Compensation
AI Innovator: $100k–$200k + equity | Principal SWE: $80k–$150k + equity
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Matterworks.ai
Staff ML Scientist
Posted 7 months, 2 weeks ago
Matterworks.ai is building AI tools and large-scale deep learning models to extract insights from biological data for therapeutic discovery, development, and manufacturing. Open roles include Principal ML Scientist, Staff ML Scientist, and Principal Software …
Tech stack
Location
Remote, Hybrid (Boston/Somerville MA)
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Recombine
Principal Software Engineer
Posted 7 months, 2 weeks ago
Recombine builds advanced conversational AI agents for Europe's banks, fintechs and marketplace companies. We're hiring a Senior Solution Engineer, a Principal Software Engineer and a Senior Infrastructure Engineer. Tech we use: TypeScript, Node.js, Python, T…
Tech stack
Location
Remote (UK/EU)
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Matterworks.ai
Staff ML Scientist
Posted 8 months, 2 weeks ago
At Matterworks we are building AI tools to extract insights from the ever-growing corpora of biological data and to unlock opportunities in therapeutic discovery, development, and manufacturing. We are building large-scale deep learning models of biological d…
Location
Remote, Hybrid